Nephrology, Internal Medicine and Kidney Diseases

Autoimmune kidney diseases and their management

Autoimmune kidney diseases, such as lupus nephritis and anti-glomerular basement membrane (GBM) disease, occur when the immune system mistakenly attacks the kidneys, leading to inflammation and damage. Management of autoimmune kidney diseases involves suppressing the immune system to reduce inflammation and prevent further kidney damage. This can be achieved through the use of immunosuppressive medications such as corticosteroids, cyclophosphamide, and mycophenolate mofetil. In severe cases, plasmapheresis or intravenous immunoglobulin (IVIG) may also be used to remove harmful antibodies from the blood. Regular monitoring of kidney function and urine protein levels is essential in managing autoimmune kidney diseases and preventing disease progression.